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PBC diagnosis was all of a sudden for me. I am 40 years of age and I believe it's a bit too early for such a serious disease. I am a bit overweight so I have been diagnosed with certain liver disorders but nothing of the kind. I have horrible itching in my legs at night and I have problems with my bowels. Recently I've been put on Ursodiol and my liver enzymes got back normal what was next to impossible as I have tried many meds and they didn't help a lot. The Ursodiol seems to work well for me. And I'm happy with it.
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Because gallbladder cancer is rare, doctors do not recommend the routine removal of gallbladders in people with asymptomatic gallstones to prevent cancer.
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Free ursodiol, 7-keto-lithocholic acid, and lithocholic acid are relatively insoluble in aqueous media and larger proportions of these compounds are lost from the distal gut into the feces.
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