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What does imiquimod cream do to warts? Imiquimod cream is used to treat certain types of actinic keratoses (flat, scaly growths on the skin caused by too much sun exposure) on the face or scalp. Imiquimod is in a class of medications called immune response modifiers. It treats genital and anal warts by increasing the activity of the body's immune system.
How long do side effects of imiquimod last? The skin reaction tends to be worst in week 2 to 3 of application. For most people, the more sore and red the skin becomes, the better the treatment works. It is normal for redness and some crusting to persist for around 2 weeks after the treatment course has finished.

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